1352064-70-0
1352064-70-0
Chemical Structure
AM-8553
- CAS No.: 1352064-70-0
- Formula:C25H29Cl2NO4
- Molecular Weight:478.41
IUPAC Name: 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
InChIKey: YUALYRLIFVPOHL-VPLUBSIMSA-N
SMILES: O=C(O)C[C@]1(C)C(N([C@@H](CC)[C@@H](O)C)[C@H](C2=CC=C(Cl)C=C2)[C@@H](C3=CC=CC(Cl)=C3)C1)=O
Biological Activity: AM-8553 is a MDM2/p53 inhibitor (KD: 0.4 nM for MDM2). AM-8553 has anti-tumor activity[1]
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AM-8553 | AM-8553 is a MDM2/p53 inhibitor (KD: 0.4 nM for MDM2). AM-8553 has anti-tumor activity | |||||||||||||||||||||
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References
Keywords
