1352608-94-6
1352608-94-6
Chemical Structure
ALK5-IN-10
- CAS No.: 1352608-94-6
- Formula:C22H18BrN7
- Molecular Weight:460.33
IUPAC Name: N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
InChIKey: SJOMJTKWXZEYKX-UHFFFAOYSA-N
SMILES: BrC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
Biological Activity: ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer[1].
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ALK5-IN-10 | ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
