135383-55-0
135383-55-0
Chemical Structure
Monomethyl auristatin E intermediate-7
- CAS No.: 135383-55-0
- Formula:C20H31NO5
- Molecular Weight:365.46
IUPAC Name: tert-butyl (3R,4S,5S)-4-(((benzyloxy)carbonyl)amino)-3-hydroxy-5-methylheptanoate
InChIKey: AZTSBAWJROLRIQ-LESCRADOSA-N
SMILES: CC[C@H](C)[C@@H]([C@@H](CC(OC(C)(C)C)=O)O)NC(OCC1=CC=CC=C1)=O
Biological Activity: Monomethyl auristatin E intermediate-7 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-7 | 99.31% | Monomethyl auristatin E intermediate-7 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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