1354198-41-6
Chemical Structure
GS-462808
- CAS No.: 1354198-41-6
- Formula:C17H12F3N5O3
- Molecular Weight:391.30
IUPAC Name: 2-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
InChIKey: CIUYUJJQZDDGTM-UHFFFAOYSA-N
SMILES: O=C1N(CC2=NC(C)=NO2)N=C3C=CC(C4=CC=C(OC(F)(F)F)C=C4)=CN31
Biological Activity: GS-462808 is an oral active late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with the IC50 of 1.33 μM. GS-462808 can be used for study of arrhythmia[1].
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GS-462808 | GS-462808 is an oral active late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with the IC50 of 1.33 μM. GS-462808 can be used for study of arrhythmia. | |||||||||||||||||||||
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Keywords