1355454-05-5
1355454-05-5
Chemical Structure
ML165
Synonym(s): RUC-2
- CAS No.: 1355454-05-5
- Formula:C17H19N7O2S
- Molecular Weight:385.44
IUPAC Name: 2-amino-N-(3-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)phenyl)acetamide
InChIKey: ITNCYPYTFKVCFI-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=C1)CN
Biological Activity: ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC50: 96 nM)[1].
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ML165 | ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC50: 96 nM). | |||||||||||||||||||||
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References
Keywords
