1357447-10-9
Chemical Structure
YopE(69-77)
- CAS No.: 1357447-10-9
- Formula:C47H79N13O12S
- Molecular Weight:1050.28
InChIKey: JTCIDAJVMYINBU-KQQRPKPCSA-N
SMILES: CSCC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@@H](NC(CNC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@@H](N)CO)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O
Biological Activity: YopE (69-77) is an H-2Kb-restricted immunodominant protective bacterial epitope that binds with high affinity to mouse H-2Kb and human HLA-A26:01 class I MHC alleles. YopE is a virulence factor derived from Yersinia pseudotuberculosis, Yersinia pestis, and serogroups O9 and O3 of Yersinia enterocolitica. YopE (69-77) can be used in studies related to Yersinia pseudotuberculosis infection[1][2].
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YopE(69-77) | YopE (69-77) is an H-2Kb-restricted immunodominant protective bacterial epitope that binds with high affinity to mouse H-2Kb and human HLA-A26:01 class I MHC alleles. YopE is a virulence factor derived from Yersinia pseudotuberculosis, Yersinia pestis, and serogroups O9 and O3 of Yersinia enterocolitica. YopE (69-77) can be used in studies related to Yersinia pseudotuberculosis infection. | |||||||||||||||||||||
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References
- [1]. Zhang Y, et al. Effector CD8+ T cells are generated in response to an immunodominant epitope in type III effector YopE during primary Yersinia pseudotuberculosis infection. Infection and immunity. 2014 Jul;82(7):3033-44.
- [2]. Zhang Y, et al. Precursor Abundance Influences Divergent Antigen-Specific CD8 T Cell Responses after Yersinia pseudotuberculosis Foodborne Infection. Infection and immunity. 2021 Jul 15;89(8):e0026521.
