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Cat. No.: HY-P12181

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YopE(69-77)

YopE (69-77) is an H-2K_b-restricted immunodominant protective bacterial epitope that binds with high affinity to mouse H-2K_b and human HLA-A26:01 class I MHC alleles. YopE is a virulence factor derived from Yersinia pseudotuberculosis, Yersinia pestis, and serogroups O9 and O3 of Yersinia enterocolitica. YopE (69-77) can be used in studies related to Yersinia pseudotuberculosis infection.

For research use only. We do not sell to patients.

CAS No.: 1357447-10-9
Formula: C₄₇H₇₉N₁₃O₁₂S
Molecular Weight:1050.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

YopE(69-77) Chemical Structure

CAS No.: 1357447-10-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

YopE(69-77) displays strong predicted binding affinity for mouse H-2Kb (IC₅₀ = 20 nM) and human HLA-A26:01 (IC₅₀ = 12 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1357447-10-9
Molecular Weight 1050.28
Formula C₄₇H₇₉N₁₃O₁₂S
Sequence

Ser-Val-Ile-Gly-Phe-Ile-Gln-Arg-Met
Sequence Shortening

SVIGFIQRM
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang Y, et al. Effector CD8+ T cells are generated in response to an immunodominant epitope in type III effector YopE during primary Yersinia pseudotuberculosis infection. Infection and immunity. 2014 Jul;82(7):3033-44.

[2]. Zhang Y, et al. Precursor Abundance Influences Divergent Antigen-Specific CD8 T Cell Responses after Yersinia pseudotuberculosis Foodborne Infection. Infection and immunity. 2021 Jul 15;89(8):e0026521.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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