1370510-16-9
1370510-16-9
Chemical Structure
Langkamide
- CAS No.: 1370510-16-9
- Formula:C16H17NO5
- Molecular Weight:303.31
IUPAC Name: (Z)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-1,5-dihydro-2H-pyrrol-2-one
InChIKey: RZTXFCPQEOFMDN-SREVYHEPSA-N
SMILES: COC1=C(C(OC)=CC(/C=C\C(N2C(C=CC2)=O)=O)=C1)OC
Biological Activity: Langkamide is a novel hypoxia-inducible factor-2 (HIF-2) inhibitory pyrrolidone alkaloid isolated from the roots and stems of Piper sarmentosum, which inhibits HIF-2 transcriptional activity with an EC value of 14.0μM.
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Langkamide | Langkamide is a novel hypoxia-inducible factor-2 (HIF-2) inhibitory pyrrolidone alkaloid isolated from the roots and stems of Piper sarmentosum, which inhibits HIF-2 transcriptional activity with an EC value of 14.0μM. | |||||||||||||||||||||
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Keywords
