1372642-78-8
Chemical Structure
KMG-301AM TFA
- CAS No.: 1372642-78-8
- Formula:C32H28F3N3O8
- Molecular Weight:639.58
IUPAC Name: N-(9-(3-((acetoxymethoxy)carbonyl)-4-oxo-4H-quinolizin-1-yl)-6-(dimethylamino)-3H-xanthen-3-ylidene)-N-methylmethanaminium 2,2,2-trifluoroacetate
InChIKey: NMFWYDTXAWHNRE-UHFFFAOYSA-M
SMILES: O=C1C(C(OCOC(C)=O)=O)=CC(C(C2=CC=C(N(C)C)C=C2O3)=C4C3=C/C(C=C4)=[N+](C)/C)=C5C=CC=CN51.[O-]C(C(F)(F)F)=O
Biological Activity: KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KMG-301AM TFA | 95.02% | KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model. | ||||||||||||||||||||
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Keywords
