1373887-29-6
1373887-29-6
Chemical Structure
ER176
Synonym(s): BIBD-239
- CAS No.: 1373887-29-6
- Formula:C20H20ClN3O
- Molecular Weight:353.85
IUPAC Name: (R)-N-(sec-butyl)-4-(2-chlorophenyl)-N-methylquinazoline-2-carboxamide
InChIKey: ASFLYNMYGAYKON-CYBMUJFWSA-N
SMILES: O=C(C1=NC(C2=CC=CC=C2Cl)=C3C=CC=CC3=N1)N(C)[C@H](C)CC
Biological Activity: ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein (TSPO), a biomarker for neuroinflammation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ER176 | 99.77% | ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein (TSPO), a biomarker for neuroinflammation. | ||||||||||||||||||||
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References
- [1]. Masahiro Fujita, et al. Comparison of four 11 C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios. EJNMMI Res. 2017 Oct 16;7(1):84. [Content Brief]
- [2]. Jason C Mixdorf, et al. Alternative strategies for the synthesis of [ 11 C]ER176 for PET imaging of neuroinflammation. Appl Radiat Isot. 2021 Sep 17;178:109954. [Content Brief]
Keywords
