1379761-16-6
Chemical Structure
Aminoxyacetamide-PEG3-azide
- CAS No.: 1379761-16-6
- Formula:C10H21N5O5
- Molecular Weight:291.30
IUPAC Name: 2-(aminooxy)-N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)acetamide
InChIKey: XAZLOCGDVCWCCY-UHFFFAOYSA-N
SMILES: NOCC(NCCOCCOCCOCCN=[N+]=[N-])=O
Biological Activity: Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminoxyacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Aminoxyacetamide-PEG3-azide | 99.82% | Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminoxyacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Keywords
