1383716-46-8
Chemical Structure
Vps34-IN-4
- CAS No.: 1383716-46-8
- Formula:C21H25N7O
- Molecular Weight:391.47
IUPAC Name: 1-((4'-(cyclopropylmethyl)-2-(pyridin-4-ylamino)-[4,5'-bipyrimidin]-2'-yl)amino)-2-methylpropan-2-ol
InChIKey: XJTIGGCBXFIZJV-UHFFFAOYSA-N
SMILES: CC(O)(C)CNC1=NC=C(C2=NC(NC3=CC=NC=C3)=NC=C2)C(CC4CC4)=N1
Biological Activity: Vps34-IN-4 (compound 19) is a potent, selective, and orally active inhibitor of VPS34. Vps34-IN-4 inhibits the autophagy in vivo. Autophagy is a dynamic process that regulates lysosomal-dependent degradation of cellular components[1].
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Vps34-IN-4 | 98.79% | Vps34-IN-4 (compound 19) is a potent, selective, and orally active inhibitor of VPS34. Vps34-IN-4 inhibits the autophagy in vivo. Autophagy is a dynamic process that regulates lysosomal-dependent degradation of cellular components. | ||||||||||||||||||||
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Keywords