1396886-30-8
1396886-30-8
Chemical Structure
VU0530244
- CAS No.: 1396886-30-8
- Formula:C22H20FN5O
- Molecular Weight:389.43
InChIKey: JWLJKHOGMOIRDR-UHFFFAOYSA-N
SMILES: O=C(N1CC(C1)C2=NC3=C(N2)C=C(C)C=C3)C4=CC(C5=CC=C(F)C=C5)=NN4C
Biological Activity: VU0530244 is a potent antagonist of 5-HT2B, with the IC50 of 17.3 nM. VU0530244 is predicted to have very limited potential for brain penetration in human subjects, as is predicted to be substrates for P-gp-mediated efflux in humans[1].
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VU0530244 | VU0530244 is a potent antagonist of 5-HT2B, with the IC50 of 17.3 nM. VU0530244 is predicted to have very limited potential for brain penetration in human subjects, as is predicted to be substrates for P-gp-mediated efflux in humans. | |||||||||||||||||||||
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References
Keywords
