139878-36-7
Chemical Structure
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine
- CAS No.: 139878-36-7
- Formula:C21H39FN2O5Si2
- Molecular Weight:474.71
IUPAC Name: 1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: NLTNXZUKPKJZQK-VDHUWJSZSA-N
SMILES: O=C(C=CN1[C@H]2[C@H](F)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)NC1=O
Biological Activity: 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine | 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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