1423719-31-6

(S)-Nerandomilast Chemical Structure
1423719-31-6

Chemical Structure

(S)-Nerandomilast

Synonym(s): (S)-BI 1015550

  • CAS No.: 1423719-31-6
  • Formula:C20H25ClN6O2S
  • Molecular Weight:448.97

IUPAC Name: (S)-2-(4-(5-chloropyrimidin-2-yl)piperidin-1-yl)-4-((1-(hydroxymethyl)cyclobutyl)amino)-6,7-dihydrothieno[3,2-d]pyrimidine 5-oxide

InChIKey: UHYCLWAANUGUMN-PMERELPUSA-N

SMILES: O=[S@@]1C2=C(CC1)N=C(N3CCC(CC3)C4=NC=C(C=N4)Cl)N=C2NC5(CO)CCC5

Biological Activity: (S)-Nerandomilast ((S)-BI 1015550) is the S-isomer of Nerandomilast (HY-153192). Nerandomilast is an orally active PDE4B inhibitor with an IC50 value of 7.2 nM. Nerandomilast has good safety profile and potential applications in inflammation, allergic diseases, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD).

Cat. No. Product Name Purity Description Pricing
HY-153192B
(S)-Nerandomilast 98.69% (S)-Nerandomilast ((S)-BI 1015550) is the S-isomer of Nerandomilast (HY-153192). Nerandomilast is an orally active PDE4B inhibitor with an IC50 value of 7.2 nM. Nerandomilast has good safety profile and potential applications in inflammation, allergic diseases, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD).
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