142523-14-6
142523-14-6
Chemical Structure
L-690488
- CAS No.: 142523-14-6
- Formula:C32H52O16P2
- Molecular Weight:754.69
IUPAC Name: (((1-(4-hydroxyphenoxy)ethane-1,1-diyl)bis(oxo-l5-phosphanetriyl))tetrakis(oxy))tetrakis(methylene) tetrakis(2,2-dimethylpropanoate)
InChIKey: LOTSPVPQHAUHCE-UHFFFAOYSA-N
SMILES: CC(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OC1=CC=C(O)C=C1
Biological Activity: L-690488 is a proagent of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor. L-690488 has more effective cell penetration than L-690330[1][2].
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L-690488 | L-690488 is a proagent of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor. L-690488 has more effective cell penetration than L-690330. | |||||||||||||||||||||
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References
- [1]. Atack JR, et al. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J Pharmacol Exp Ther. 1994 Jul;270(1):70-6. [Content Brief]
- [2]. Chen X, et al. Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1. Am J Physiol. 1998 Aug;275(2):E272-7. [Content Brief]
Keywords
