1432729-22-0
Chemical Structure
MK-8768
- CAS No.: 1432729-22-0
- Formula:C21H22F3N5O2
- Molecular Weight:433.43
InChIKey: KTYWQIWONODXST-CWTRNNRKSA-N
SMILES: NC(C1=NC2=CC(CN3C[C@H](C(F)(F)F)O[C@H](C)C3)=CC=C2C(C4=CN(C)N=C4)=C1)=O
Biological Activity: MK-8768 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 .6nM) with excellent brain permeability.
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MK-8768 | 99.56% | MK-8768 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 .6nM) with excellent brain permeability. | ||||||||||||||||||||
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Keywords