143816-42-6
143816-42-6
Chemical Structure
Quininib
- No. CAS: 143816-42-6
- Formula:C17H13NO
- Molecular Weight:247.29
IUPAC Name: (E)-2-(2-(quinolin-2-yl)vinyl)phenol
InChIKey: NXNDEWNGCMCWMA-ZRDIBKRKSA-N
SMILES: OC1=CC=CC=C1/C=C/C2=NC3=CC=CC=C3C=C2
Biological Activity: Quininib is a cysteinyl leukotriene 1 and 2 receptor antagonist with IC50s of 1.2 and 52 μM for CysLT1R and CysLT2R, respectively. Quininib is a potent inhibitor of developmental angiogenesis in the zebrafish eye. Quininib can be used for the research of ocular neovascular pathologies and may complement current anti-VEGF biological agents[1].
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Quininib | 98.1% | Quininib is a cysteinyl leukotriene 1 and 2 receptor antagonist with IC50s of 1.2 and 52 μM for CysLT1R and CysLT2R, respectively. Quininib is a potent inhibitor of developmental angiogenesis in the zebrafish eye. Quininib can be used for the research of ocular neovascular pathologies and may complement current anti-VEGF biological agents. | ||||||||||||||||||||
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References
Keywords
