1440755-31-6
Chemical Structure
Atrovastatin-PEG3-FITC
- CAS No.: 1440755-31-6
- Formula:C64H68FN5O12S
- Molecular Weight:1150.31
IUPAC Name: 1-((19R,21R)-1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)amino)-19,21-dihydroxy-17-oxo-1-thioxo-6,9,12-trioxa-2,16-diazatricosan-23-yl)-5-(4-fluorophenyl)-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide
InChIKey: WHWNHUTWCMCCLV-YYACYCFASA-N
SMILES: O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC=C(NC(NCCCOCCOCCOCCCNC(C[C@H](O)C[C@H](O)CCN6C(C7=CC=C(C=C7)F)=C(C8=CC=CC=C8)C(C(NC9=CC=CC=C9)=O)=C6C(C)C)=O)=S)C=C51
Biological Activity: Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Atrovastatin-PEG3-FITC | 99.23% | Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay. | ||||||||||||||||||||
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- [1]. Gunther Zimmermann, et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signaling. Nature. 2013 May 30;497(7451):638-42. [Content Brief]
- [2]. Yan Jiang, et al. Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors. J Med Chem. 2017 Nov 22;60(22):9400-9406. [Content Brief]
Keywords
