1446324-05-5
1446324-05-5
Chemical Structure
c-Met-IN-11
- CAS No.: 1446324-05-5
- Formula:C30H20F2N4O3
- Molecular Weight:522.50
IUPAC Name: 5-((3-fluoro-4-((7-methoxyquinolin-4-yl)oxy)phenyl)amino)-3-(4-fluorophenyl)-1,6-naphthyridin-4(1H)-one
InChIKey: TYOVUEVLYPWSPH-UHFFFAOYSA-N
SMILES: COC1=CC2=NC=CC(OC3=C(C=C(C=C3)NC4=C5C(C(C6=CC=C(C=C6)F)=CNC5=CC=N4)=O)F)=C2C=C1
Biological Activity: c-Met-IN-11 (compound 3) is a potent c-MET and VEGFR-2 inhibitor, with IC50 values of 41.4 and 71.1 nM, respectively[1].
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c-Met-IN-11 | c-Met-IN-11 (compound 3) is a potent c-MET and VEGFR-2 inhibitor, with IC50 values of 41.4 and 71.1 nM, respectively. | |||||||||||||||||||||
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References
Keywords
