144924-81-2
144924-81-2
Chemical Structure
2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine
- CAS No.: 144924-81-2
- Formula:C12H16FN5O3
- Molecular Weight:297.29
IUPAC Name: (2R,3R,4S,5R)-5-(6-(dimethylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: VYOFGEWTSVZOGF-MCOZSMFQSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N2C(N=CN=C3N(C)C)=C3N=C2)O[C@@H]1CO
Biological Activity: 2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine | 2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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