1453208-66-6
Chemical Structure
ASP5878
- CAS No.: 1453208-66-6
- Formula:C18H19F2N5O4
- Molecular Weight:407.37
IUPAC Name: 2-(4-((5-((2,6-difluoro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)ethan-1-ol
InChIKey: VDZZYOJYLLNBTD-UHFFFAOYSA-N
SMILES: OCCN1N=CC(NC2=NC=C(OCC3=C(F)C(OC)=CC(OC)=C3F)C=N2)=C1
Biological Activity: ASP5878 is an oral active inhibitor of FGFR 1, 2, 3, and 4, with IC50 values of 0.47 nM, 0.6 nM, 0.74 nM and 3.5 nM for FGFR 1, 2, 3, and 4 kinase activity. ASP5878 has potential antineoplastic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASP5878 | 99.69% | ASP5878 is an oral active inhibitor of FGFR 1, 2, 3, and 4, with IC50 values of 0.47 nM, 0.6 nM, 0.74 nM and 3.5 nM for FGFR 1, 2, 3, and 4 kinase activity. ASP5878 has potential antineoplastic activity. | ||||||||||||||||||||
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Keywords