147149-76-6
147149-76-6
Chemical Structure
Nolatrexed
Synonym(s): AG 337 free base
- CAS No.: 147149-76-6
- Formula:C14H12N4OS
- Molecular Weight:284.34
IUPAC Name: 2-amino-6-methyl-5-(pyridin-4-ylthio)quinazolin-4(1H)-one
InChIKey: XHWRWCSCBDLOLM-UHFFFAOYSA-N
SMILES: O=C1N=C(NC2=CC=C(C)C(SC3=CC=NC=C3)=C12)N
Biological Activity: Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.
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Nolatrexed | Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils. | |||||||||||||||||||||
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Keywords
