1492060-44-2
1492060-44-2
Chemical Structure
5-LO/mPGES1-IN-1
- CAS No.: 1492060-44-2
- Formula:C25H25ClN4O2S2
- Molecular Weight:513.07
IUPAC Name: 2-((4-chloro-6-((4-(naphthalen-2-yl)thiazol-2-yl)amino)pyrimidin-2-yl)thio)octanoic acid
InChIKey: BADFIDKPYNKNRT-UHFFFAOYSA-N
SMILES: O=C(C(CCCCCC)SC1=NC(Cl)=CC(NC2=NC(C3=CC4=C(C=CC=C4)C=C3)=CS2)=N1)O
Biological Activity: 5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO). IC50 values are 0.3 and 0.4 μM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-LO/mPGES1-IN-1 | 99.00% | 5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO). IC50 values are 0.3 and 0.4 μM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity. | ||||||||||||||||||||
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References
Keywords
