151140-96-4
151140-96-4
Chemical Structure
Avitriptan
Synonym(s): BMS 180048
- CAS No.: 151140-96-4
- Formula:C22H30N6O3S
- Molecular Weight:458.58
IUPAC Name: 1-(3-(3-(4-(5-methoxypyrimidin-4-yl)piperazin-1-yl)propyl)-1H-indol-5-yl)-N-methylmethanesulfonamide
InChIKey: WRZVGHXUPBWIOO-UHFFFAOYSA-N
SMILES: O=S(NC)(CC1=CC2=C(NC=C2CCCN3CCN(CC3)C4=C(OC)C=NC=N4)C=C1)=O
Biological Activity: Avitriptan is a 5-HT1B/1D receptor agonist, with pKis of 7.44 ( 5-HT1B rat), 7.68 ( 5-HT1B human) and 8.36 ( 5-HT1D human). Avitriptan constricts the isolated coronary artery. Avitriptan can be used for migraines[1].
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Avitriptan | Avitriptan is a 5-HT1B/1D receptor agonist, with pKis of 7.44 ( 5-HT1B rat), 7.68 ( 5-HT1B human) and 8.36 ( 5-HT1D human). Avitriptan constricts the isolated coronary artery. Avitriptan can be used for migraines. | |||||||||||||||||||||
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References
Keywords
