151898-26-9
Chemical Structure
8-Br-cADPR
Synonym(s): 8-Bromo-Cyclic ADP-Ribose
- CAS No.: 151898-26-9
- Formula:C15H20BrN5O13P2
- Molecular Weight:620.20
InChIKey: JXKOMYPWJIFQCQ-AIKIOGRUSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CN([C@H]4[C@H](O)[C@H](O)[C@@H](COP(O5)(O)=O)O4)C3=N)O[C@@H]1COP5(O)=O
Biological Activity: 8-Br-cADPR (8-Bromo-Cyclic ADP-Ribose), a cyclic adenosine diphosphate (ADP)-ribose (cADPR) antagonist, is a TRPM2 ion channel antagonist. 8-Br-cADPR reduces renal damage and the expression of caspase-3 and TRPM2[1].
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8-Br-cADPR | 8-Br-cADPR (8-Bromo-Cyclic ADP-Ribose), a cyclic adenosine diphosphate (ADP)-ribose (cADPR) antagonist, is a TRPM2 ion channel antagonist. 8-Br-cADPR reduces renal damage and the expression of caspase-3 and TRPM2. | |||||||||||||||||||||
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Keywords