1519043-97-0
1519043-97-0
Chemical Structure
YCW-E11
- CAS No.: 1519043-97-0
- Formula:C25H21Cl2N3O6S2
- Molecular Weight:594.49
IUPAC Name: N-(2-(3-(3,5-dichlorophenyl)ureido)ethyl)-3-(2-(3,4-dihydroxyphenoxy)phenyl)thiophene-2-sulfonamide
InChIKey: WGQUHJXSXSEWBH-UHFFFAOYSA-N
SMILES: O=C(NCCNS(=O)(C1=C(C2=C(OC3=CC=C(C(O)=C3)O)C=CC=C2)C=CS1)=O)NC4=CC(Cl)=CC(Cl)=C4
Biological Activity: YCW-E11 is a Bcl-2, and Mcl-1 inhibitor with Ki values of 0.83 and 0.33 μM, respectively. YCW-E11 induces cell apoptosis through the mitochondrial pathway and exhibits antitumor activity. YCW-E11 can be utilized in cancer research[1].
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YCW-E11 | YCW-E11 is a Bcl-2, and Mcl-1 inhibitor with Ki values of 0.83 and 0.33 μM, respectively. YCW-E11 induces cell apoptosis through the mitochondrial pathway and exhibits antitumor activity. YCW-E11 can be utilized in cancer research. | |||||||||||||||||||||
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References
Keywords
