153232-60-1
Chemical Structure
9-Amino-NeuAc
- CAS No.: 153232-60-1
- Formula:C11H20N2O8
- Molecular Weight:308.29
IUPAC Name: (2S,4S,5R,6R)-5-acetamido-6-((1R,2R)-3-amino-1,2-dihydroxypropyl)-2,4-dihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: PSFLJKJWZHEYMD-PFQGKNLYSA-N
SMILES: O[C@@H]([C@@](O[C@]1(O)C(O)=O)([H])[C@@H]([C@H](C1)O)NC(C)=O)[C@H](O)CN
Biological Activity: 9-Amino-NeuAc is a substrate of synthase. 9-Amino-NeuAc can be converted to CMP9-amino-NeuAc, activated to the corresponding CMPglycoside and transferred to asialoglycoprotein. 9-Amino-NeuAc can be used to target liposome synthesis while modulating tumor surface immunogenicity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
9-Amino-NeuAc | 98.92% | 9-Amino-NeuAc is a substrate of synthase. 9-Amino-NeuAc can be converted to CMP9-amino-NeuAc, activated to the corresponding CMPglycoside and transferred to asialoglycoprotein. 9-Amino-NeuAc can be used to target liposome synthesis while modulating tumor surface immunogenicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Zheng N, et al. Liposome-aided metabolic engineering of tumor surface immunogenicity. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2550-2554. [Content Brief]
- [2]. Gross H J, et al. Asialo-伪 1-acid glycoprotein resialylated with 9-amino-5-N-acetyl-d-neuraminic acid is resistant towards bacterial, viral and mammalian sialidases[J]. Glycoconjugate Journal, 1988, 5: 411-417.
Keywords
