153314-49-9
Chemical Structure
LP-130
- CAS No.: 153314-49-9
- Formula:C45H58N6O7
- Molecular Weight:794.98
IUPAC Name: (3S,4S)-4-((S)-2-((S)-2-acetamido-3-(naphthalen-1-yl)propanamido)-3-methylbutanamido)-N-((S)-1-(((S)-1-amino-3-(naphthalen-1-yl)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)-3-hydroxy-6-methylheptanamide
InChIKey: ACPDNLLISIAERE-ZYWZKTPASA-N
SMILES: NC([C@H](CC1=CC=CC2=C1C=CC=C2)NC([C@H](CC)NC(C[C@H](O)[C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC3=CC=CC4=C3C=CC=C4)=O)=O)=O)=O)=O
Biological Activity: LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition.
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LP-130 | LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition. | |||||||||||||||||||||
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Keywords
