153549-84-9
![[D-Trp34]-Neuropeptide Y Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p1322.gif "[D-Trp34]-Neuropeptide Y Chemical Structure")
153549-84-9
Chemical Structure
[D-Trp34]-Neuropeptide Y
- CAS No.: 153549-84-9
- Formula:C196H289N55O56
- Molecular Weight:4311.72
SMILES: [YPSKPDNPGEDAPAEDLARYYSALRHYINLITR-{D-Trp}-RY-NH2]
Biological Activity: [D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats[1][2].
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[D-Trp34]-Neuropeptide Y | 99.70% | [D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats. | ||||||||||||||||||||
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References
- [1]. E M Parker, et al. [D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake. Peptides. 2000 Mar;21(3):393-9. [Content Brief]
- [2]. Bernard Beck, et al. Responsiveness of obese Zucker rats to [D-Trp34]-NPY supports the targeting of Y5 receptor for obesity treatment. Nutr Neurosci. Oct-Dec 2007;10(5-6):211-4. [Content Brief]
Keywords
