1537187-53-3
Chemical Structure
Carfilzomib-d8
- CAS No.: 1537187-53-3
- Formula:C40H49D8N5O7
- Molecular Weight:727.96
IUPAC Name: (S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-(morpholino-d8)acetamido)-4-phenylbutanamido)pentanamide
InChIKey: BLMPQMFVWMYDKT-HEMZLDBQSA-N
SMILES: O=C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@@H](NC(CN2C([2H])(C([2H])(OC([2H])(C2([2H])[2H])[2H])[2H])[2H])=O)CCC3=CC=CC=C3)=O)=O)=O)CC(C)C)[C@@]4(OC4)C
Biological Activity: Carfilzomib-d8 is deuterium labeled Carfilzomib. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.
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Carfilzomib-d8 | 98.73% | Carfilzomib-d8 is deuterium labeled Carfilzomib. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells. | ||||||||||||||||||||
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Carfilzomib (Standard) | 99.98% | Carfilzomib (Standard) is the analytical standard of Carfilzomib. This product is intended for research and analytical applications. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells. | ||||||||||||||||||||
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Carfilzomib | 99.95% | Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells. | ||||||||||||||||||||
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