15379-29-0
15379-29-0
Chemical Structure
2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine
- CAS No.: 15379-29-0
- Formula:C9H9FN2O4
- Molecular Weight:228.18
IUPAC Name: 5-fluoro-1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: SHVSSJHFEDAZCZ-CAHLUQPWSA-N
SMILES: OC[C@@H]1C=C[C@H](N(C(N2)=O)C=C(F)C2=O)O1
Biological Activity: 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine | 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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