153982-38-8
153982-38-8
Chemical Structure
JKC 302
- CAS No.: 153982-38-8
- Formula:C30H42N6O6
- Molecular Weight:582.69
InChIKey: FLVWONZBLRGQPK-VCDBXAJLSA-N
SMILES: O=C(N[C@@H](C(N1[C@](CCC1)([H])C(N[C@@H](C(N[C@H](C(N2)=O)CC(C)C)=O)C(C)C)=O)=O)CO)[C@H]2CC3=CNC4=CC=CC=C34
Biological Activity: JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring[1][2].
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JKC 302 | JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring. | |||||||||||||||||||||
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References
- [1]. Basilico N, et al. The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1. J Biomed Biotechnol. 2010;2010:854927. [Content Brief]
- [2]. Tiequn HUANG, et al. Role of endothelin and nitric oxide in the pathogenesis of asthma. Chinese Journal of Pathophysiology ; (12): 435-437, 2001.
Keywords
