156707-43-6
156707-43-6
Chemical Structure
FTase-IN-2
- CAS No.: 156707-43-6
- Formula:C15H21N3O4S2
- Molecular Weight:371.47
IUPAC Name: (4-((R)-2-amino-3-mercaptopropanamido)benzoyl)-L-methionine
InChIKey: QZVAZQOXHOMYJF-RYUDHWBXSA-N
SMILES: N(C([C@H](CS)N)=O)C1=CC=C(C(N[C@@H](CCSC)C(O)=O)=O)C=C1
Biological Activity: FTase-IN-2 (Compound 2) is a farnesyltransferase inhibitor, with IC50 values of 150 nM and 1500 nM against FTase and GGTase I, respectively. FTase-IN-2 is not farnesylated by FTase, thus avoiding metabolic inactivation[1].
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FTase-IN-2 | FTase-IN-2 (Compound 2) is a farnesyltransferase inhibitor, with IC50 values of 150 nM and 1500 nM against FTase and GGTase I, respectively. FTase-IN-2 is not farnesylated by FTase, thus avoiding metabolic inactivation. | |||||||||||||||||||||
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References
Keywords
