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Cat. No.: HY-128037

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FTase-IN-2

FTase-IN-2 (Compound 2) is a farnesyltransferase inhibitor, with IC₅₀ values of 150 nM and 1500 nM against FTase and GGTase I, respectively. FTase-IN-2 is not farnesylated by FTase, thus avoiding metabolic inactivation.

For research use only. We do not sell to patients.

CAS No.: 156707-43-6
Formula: C₁₅H₂₁N₃O₄S₂
Molecular Weight:371.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

FTase-IN-2 Chemical Structure

CAS No.: 156707-43-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 156707-43-6
Molecular Weight 371.47
Formula C₁₅H₂₁N₃O₄S₂
SMILES

N(C([C@H](CS)N)=O)C1=CC=C(C(N[C@@H](CCSC)C(O)=O)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Vogt A, et al. A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing. The Journal of biological chemistry. 1995 Jan 13;270(2):660-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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