1567657-46-8
1567657-46-8
Chemical Structure
HIF-PHD-IN-1
- CAS No.: 1567657-46-8
- Formula:C17H12Cl2N6O3
- Molecular Weight:419.22
IUPAC Name: (S)-1-(1-(1-(2,5-dichlorophenyl)ethyl)-7-oxo-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-1H-pyrazole-4-carboxylic acid
InChIKey: BJMKDEGQDAVFGT-QMMMGPOBSA-N
SMILES: O=C(C1=CN(C2=NC3=C(N([C@H](C4=CC(Cl)=CC=C4Cl)C)N=C3)C(N2)=O)N=C1)O
Biological Activity: HIF-PHD-IN-1 is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), with an IC50 of 54 nM for hHIF-PHD2. HIF-PHD-IN-1 is promising therapeutic agents for renal anemia[1].
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HIF-PHD-IN-1 | 98.84% | HIF-PHD-IN-1 is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), with an IC50 of 54 nM for hHIF-PHD2. HIF-PHD-IN-1 is promising therapeutic agents for renal anemia. | ||||||||||||||||||||
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References
Keywords
