157824-23-2
157824-23-2
Chemical Structure
R-84760
- CAS No.: 157824-23-2
- Formula:C19H25Cl3N2OS
- Molecular Weight:435.84
IUPAC Name: ((S)-5,6-dichloro-2,3-dihydro-1H-inden-1-yl)((R)-3-(pyrrolidin-1-ylmethyl)thiomorpholino)methanone hydrochloride
InChIKey: KSUNRZWFIKXTKO-LIOBNPLQSA-N
SMILES: O=C([C@H]1CCC2=C1C=C(Cl)C(Cl)=C2)N3[C@H](CN4CCCC4)CSCC3.Cl
Biological Activity: R-84760 is a selective κ-opioid receptor agonist. R-84760 has antinociceptive effect[1][2].
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R-84760 | R-84760 is a selective κ-opioid receptor agonist. R-84760 has antinociceptive effect. | |||||||||||||||||||||
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References
- [1]. Fujibayashi K, et al. Pharmacological properties of R-84760, a novel kappa-opioid receptor agonist.[J].European Journal of Pharmacology, 1994, 261(1-2):133-140.
- [2]. Fujibayashi K, et al. Profiles of the antinociceptive effect of R-84760, a selective kappa-opioid receptor agonist, in the formalin test in mice. Jpn J Pharmacol. 1995 May;68(1):57-63. [Content Brief]
Keywords
