158018-53-2
Chemical Structure
4-Epianhydrochlortetracycline hydrochloride
- CAS No.: 158018-53-2
- Formula:C22H22Cl2N2O7
- Molecular Weight:497.33
IUPAC Name: (4R,4aS,12aS)-7-chloro-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide hydrochloride
InChIKey: WIOSVFADOBZUQR-PXAZKYFKSA-N
SMILES: O[C@]12[C@](CC(C(C2=O)=C(C3=C(O)C=C4)O)=C(C)C3=C4Cl)([H])[C@H](C(O)=C(C1=O)C(N)=O)N(C)C.Cl
Biological Activity: 4-Epianhydrochlortetracycline hydrochloride is an inhibitor of matrix metalloproteinases (MMPs), particularly gelatinase B (Gelatinase B, EC 3.4.24.35), with inhibition rates of 100% at 500 μg/mL, 70% at 125 μg/mL, and 40% at 31 μg/mL. 4-Epianhydrochlortetracycline hydrochloride is promising for research in chronic inflammatory diseases[1].
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4-Epianhydrochlortetracycline hydrochloride | 4-Epianhydrochlortetracycline hydrochloride is an inhibitor of matrix metalloproteinases (MMPs), particularly gelatinase B (Gelatinase B, EC 3.4.24.35), with inhibition rates of 100% at 500 μg/mL, 70% at 125 μg/mL, and 40% at 31 μg/mL. 4-Epianhydrochlortetracycline hydrochloride is promising for research in chronic inflammatory diseases. | |||||||||||||||||||||
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