1584647-27-7
1584647-27-7
Chemical Structure
BMS-986115
Synonym(s): Notch inhibitor 1
- CAS No.: 1584647-27-7
- Formula:C26H25F7N4O3
- Molecular Weight:574.49
IUPAC Name: (2R,3S)-N1-((S)-5-(3-fluorophenyl)-9-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide
InChIKey: SRJNRAQUSAVENA-GSHUGGBRSA-N
SMILES: O=C(N[C@@H]1C(NC2=C(C)C=CC=C2C(C3=CC=CC(F)=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O
Biological Activity: BMS-986115 (Notch inhibitor 1) is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BMS-986115 | 99.90% | BMS-986115 (Notch inhibitor 1) is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer. | ||||||||||||||||||||
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References
Keywords
