160662-30-6
Chemical Structure
Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu)
- CAS No.: 160662-30-6
- Formula:C38H62N10O7
- Molecular Weight:770.96
InChIKey: YGBGAOZDOXNVRS-NXUCNJKMSA-N
SMILES: O=C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@H](C(N[C@H]3CC(C)C)=O)C(C)(C)C)=O)=O)=O)[C@H](CCCNC(N)=N)NC3=O
Biological Activity: Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) is a cyclic peptide. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) shows extremely low affinity for rat NTS1 expressed in cells (pKi < 4), whereas its semi-purified sample (Batch 2) exhibits moderate affinity for NTS1 (pKi = 5.83), a phenomenon attributed to contamination by an active linear peptide variant. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) can be used in research on neurological diseases[1].
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Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) | Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) is a cyclic peptide. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) shows extremely low affinity for rat NTS1 expressed in cells (pKi < 4), whereas its semi-purified sample (Batch 2) exhibits moderate affinity for NTS1 (pKi = 5.83), a phenomenon attributed to contamination by an active linear peptide variant. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) can be used in research on neurological diseases. | |||||||||||||||||||||
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Keywords
