160790-21-6
Chemical Structure
HER2/neu (654-662) GP2
- CAS No.: 160790-21-6
- Formula:C42H77N9O11
- Molecular Weight:884.11
IUPAC Name: L-isoleucyl-L-isoleucyl-L-seryl-L-alanyl-L-valyl-L-valylglycyl-L-isoleucyl-L-leucine
InChIKey: XQIXDDUJIUUELO-JZOOTMHBSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].
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HER2/neu (654-662) GP2 | 98.26% | HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers. | ||||||||||||||||||||
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- [1]. Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306. [Content Brief]
- [2]. Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4. [Content Brief]
Keywords