1610781-17-3
1610781-17-3
Chemical Structure
N7-Methyl-2’-deoxy-2’-fluoroarabinoguanosine
- CAS No.: 1610781-17-3
- Formula:C11H14FN5O4
- Molecular Weight:299.26
IUPAC Name: 9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methyl-1,9-dihydro-6H-purin-6-one
InChIKey: IJEIRRMHAKCXSO-GQTRHBFLSA-N
SMILES: [O-]C1=NC(N)=NC2=C1[N+](C)=CN2[C@H]3[C@@H](F)[C@H](O)[C@@H](CO)O3
Biological Activity: N7-Methyl-2’-deoxy-2’-fluoroarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N7-Methyl-2’-deoxy-2’-fluoroarabinoguanosine | N7-Methyl-2’-deoxy-2’-fluoroarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
