1613458-78-8
1613458-78-8
Chemical Structure
GSK-2793660
- CAS No.: 1613458-78-8
- Formula:C20H28ClN3O3
- Molecular Weight:393.91
IUPAC Name: (S,E)-4-amino-N-(6-(indolin-1-yl)-6-oxohex-4-en-3-yl)tetrahydro-2H-pyran-4-carboxamide hydrochloride
InChIKey: WZTHSMHCYITKEX-YNOPKORFSA-N
SMILES: NC1(C(N[C@@H](CC)/C=C/C(N2CCC3=C2C=CC=C3)=O)=O)CCOCC1.[H]Cl
Biological Activity: GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 can be used for the research of bronchiectasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK-2793660 | 99.91% | GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 can be used for the research of bronchiectasis. | ||||||||||||||||||||
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References
- [1]. Szcześniak P, et al. The Synthesis of α,α-Disubstituted α-Amino Acids via Ichikawa Rearrangement. J Org Chem. 2016;81(3):1057-1074. [Content Brief]
- [2]. Miller BE, et al. Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660). Br J Clin Pharmacol. 2017;83(12):2813-2820. [Content Brief]
Keywords
