161660-94-2
Chemical Structure
BOC-(1R,3S)-3-aminocyclopentane carboxylic acid
Synonym(s): (1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
- CAS No.: 161660-94-2
- Formula:C11H19NO4
- Molecular Weight:229.28
IUPAC Name: (1R,3S)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid
InChIKey: RNJQBGXOSAQQDG-SFYZADRCSA-N
SMILES: OC([C@@H]1CC[C@H](NC(OC(C)(C)C)=O)C1)=O
Biological Activity: BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BOC-(1R,3S)-3-aminocyclopentane carboxylic acid | 98.0% | BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research. | ||||||||||||||||||||
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