1619994-68-1
1619994-68-1
Chemical Structure
GSK2801
- CAS No.: 1619994-68-1
- Formula:C20H21NO4S
- Molecular Weight:371.45
IUPAC Name: 1-(1-(2-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethan-1-one
InChIKey: KHWCPNJRJCNVRI-UHFFFAOYSA-N
SMILES: O=C(C)C1=CC(C2=C(S(=O)(C)=O)C=CC=C2)=C3N1C=CC(OCCC)=C3
Biological Activity: GSK2801, a chemical probe, is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK2801 | 99.86% | GSK2801, a chemical probe, is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4. | ||||||||||||||||||||
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References
Keywords
