1627902-21-9

JNJ-54175446 Chemical Structure
1627902-21-9

Chemical Structure

JNJ-54175446

  • CAS No.: 1627902-21-9
  • Formula:C18H13ClF4N6O
  • Molecular Weight:440.78

IUPAC Name: (R)-(2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyrimidin-2-yl)-4-methyl-1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)methanone

InChIKey: CWFVVQFVGMFTBD-SECBINFHSA-N

SMILES: ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F

Biological Activity: JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.

Cat. No. Product Name Purity Description Pricing
HY-117508 		JNJ-54175446 98.84% JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Keywords