1629605-31-7
1629605-31-7
Chemical Structure
Domagrozumab
Synonym(s): PF-06252616
- CAS No.: 1629605-31-7
- Formula:N/A
- Molecular Weight:(143.96 kDa)
SMILES: [Domagrozumab]
Biological Activity: Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD)[1].
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Domagrozumab | 96.34% | Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD). | ||||||||||||||||||||
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References
- [1]. St Andre M, et, al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25. [Content Brief]
Keywords
