1635405-90-1
1635405-90-1
Chemical Structure
1D-2
- CAS No.: 1635405-90-1
- Formula:C20H16FN7
- Molecular Weight:373.40
IUPAC Name: 7-fluoro-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-1H-imidazo[4,5-b]pyrazin-1-yl)ethyl)quinoline
InChIKey: SXWUXXWVCWEUTA-UHFFFAOYSA-N
SMILES: FC=1C=C2N=CC=CC2=CC1C(N3C=NC=4N=CC(=NC43)C=5C=NN(C5)C)C
Biological Activity: 1D-2 is a c-Met protein kinase inhibitor, with a human-derived IC50 of 1.45 nM. 1D-2 inhibits the proliferation of cancer cells and exhibits metabolic stability in human and rat liver microsomes. 1D-2 can be used in related research on non-small cell lung cancer[1].
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1D-2 | 1D-2 is a c-Met protein kinase inhibitor, with a human-derived IC50 of 1.45 nM. 1D-2 inhibits the proliferation of cancer cells and exhibits metabolic stability in human and rat liver microsomes. 1D-2 can be used in related research on non-small cell lung cancer. | |||||||||||||||||||||
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