1638100-63-6
Chemical Structure
KSK120
- CAS No.: 1638100-63-6
- Formula:C28H22N2O2S
- Molecular Weight:450.55
IUPAC Name: 8-cyclopropyl-7-(naphthalen-1-ylmethyl)-5-oxo-N-phenyl-5H-thiazolo[3,2-a]pyridine-3-carboxamide
InChIKey: TYPJPKPPPMYZMM-UHFFFAOYSA-N
SMILES: O=C(C=C1CC2=CC=CC3=C2C=CC=C3)N4C(C(NC5=CC=CC=C5)=O)=CSC4=C1C6CC6
Biological Activity: KSK120 is a potent inhibitor of drug-resistant infections with specific activity against Chlamydia trachomatis (C. trachomatis). KSK120 inhibits the developmental cycle of C. trachomatis, thereby reducing the infectivity of progeny bacteria. KSK120 targets the glucose-6-phosphate (G-6P) metabolic pathway of C. trachomatis, showing its potential application in antimicrobial inhibition. The mechanism of KSK120 may involve inhibition of the transcriptional machinery, which provides new ideas for the development of specific drugs against C. trachomatis infection[1].
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KSK120 | KSK120 is a potent inhibitor of drug-resistant infections with specific activity against Chlamydia trachomatis (C. trachomatis). KSK120 inhibits the developmental cycle of C. trachomatis, thereby reducing the infectivity of progeny bacteria. KSK120 targets the glucose-6-phosphate (G-6P) metabolic pathway of C. trachomatis, showing its potential application in antimicrobial inhibition. The mechanism of KSK120 may involve inhibition of the transcriptional machinery, which provides new ideas for the development of specific drugs against C. trachomatis infection. | |||||||||||||||||||||
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Keywords
