1643538-19-5
1643538-19-5
Chemical Structure
3-Ethylaniline-d5
- CAS No.: 1643538-19-5
- Formula:C8H6D5N
- Molecular Weight:126.21
IUPAC Name: 3-(ethyl-d5)aniline
InChIKey: AMKPQMFZCBTTAT-ZBJDZAJPSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])C1=CC(N)=CC=C1
Biological Activity: 3-Ethylaniline-d5 is the deuterium labeled 3-Ethylaniline (HY-W010482). 3-Ethylaniline is metabolized in vivo to electrophilic intermediates that covalently bind to DNA and that adducts are formed in the DNA of bladder. 3-Ethylaniline can be used for the research of bladder cancer[1][2].
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3-Ethylaniline-d5 | 3-Ethylaniline-d5 is the deuterium labeled 3-Ethylaniline (HY-W010482). 3-Ethylaniline is metabolized in vivo to electrophilic intermediates that covalently bind to DNA and that adducts are formed in the DNA of bladder. 3-Ethylaniline can be used for the research of bladder cancer. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
- [2]. Paul L Skipper, et al. DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice. Chem Res Toxicol. 2006 Aug;19(8):1086-90. [Content Brief]
Keywords
